Credit hours
In-class work per week |
Practice per week |
Credits |
Duration |
Total |
3 |
2 |
8 |
15 weeks |
120 hours |
Instructor
Claudia Barros Monteiro Vitorello
Luis Eduardo Aranha Camargo
Objective
Provide students with actual knowledge on defense and attack mechanisms of plants and pathogens in
order to elaborate strategies of genetic control of diseases.
Content
Genetic resistance: many terms for a complex phenomenon. Non-host and host resistance. Resistance
as a stratified and coordinated response: a paradigm. Flor´s gene-for-gene Theory. The molecular
interpretation of Flor´s Theory - the R genes. R x Avr interaction: the receptor-ligand and guard models.
R genes:genomic organization and evolution. Evolutionary convergence between pathogen recognition
systems of animals and plants. Systemic acquired resistance (SAR) and Induced systemic resistance
(ISR). Necrotrophic brute-force, stealthy necrotrophic and non-necrotrophic pathogens. Virulence,
adaptative and pathogenicity genes. Effector molecules: virulence and avirulence proteins - but how?
New approaches to identify resistance and pathogenicity mechanisms. Breeding for resistance:
qualitative and quantitative resistances. Breeding for resistance:peculiarities. Durability of resistance
genes. Strategies for using R genes: multi-lines (mixtures), pyramids and rotation of vertical genes.
Transgenic approaches for the genetic control of diseases.
Bibliography
Due to the constant progresses in this field, bibliography is based on scientific articles extracted from internationals. As such, references are updated every time the course is offered.