Course - detail

LGN5705 - Population Genetics


Credit hours

In-class work
per week
Practice
per week
Credits
Duration
Total
4
0
8
15 weeks
120 hours

Instructor
Giancarlo Conde Xavier Oliveira

Objective
The main objective of the course is to present and discuss the theoretical foundations of Population Genetics and its applications for Conservation Biology and Plant Breeding, conveying a global view of the mechanisms involved in the dynamics of genes in natural and artificial populations.

Content
Introduction to Population Genetics. Genetic constitution of populations. Genotypic and genic frequencies. Population genetics analysis utizing genetic markers. Hardy-Weinberg equilibrium. Reproductive systems, including crossing systems. Wright equilibrium. Estimation of parameters indicating plant reproductive systems. Regular inbreeding systems and coefficients of kinship. Genetic drift. Population effective size. Genetic structure of natural and artificial populations. Wright's F statistics and further developments. Mutation. Mutation-drift interactions. Gene flow and population history. Gene flow-drift interactions. Selection. Interactions with selection. More complex types of selection. Measures of genetic diversity.

Bibliography
ALLENDORF, F.; LUIKART G. Conservation and the Genetics of Populations. Blackwell Publishing, Oxford, UK, 2007. 642p.
CROW, F.; KIMURA, M. An Introduction to Population Genetics Theory. Harper & Row Publishers, New York, NY, USA, 1970.
CUTTER, Asher D. 2019. A Primer of Molecular Population Genetics. Oxford University Press. Oxford, UK.
FALCONER, D.S. & MACKAY, T. Introduction to Quantitative Genetics. 4rd ed. Longman Scientific & Technical, London, UK, 1996.
FUTUYMA, D.J. Evolutionary Biology. 3rd ed. Sinauer Associates, Sunderland, MA, USA, 2006. 763p.
GILLESPIE, J.H. Population Genetics: A Concise Guide. 2ª ed. Johns Hopkins University Press, Baltimore, MD, USA, 2004. 232p.
HARTL, D.L. A primer of Population Genetics. 3rd ed. Sinauer Associates, Sunderland, MA, USA, 2000. 221p.
HARTL, D.L. & CLARK, A.G. Principios de Genética de Populações, 4ª ed. ArtMed Editora, Porto Alegre, RS, 2010. 217p.
HEDRICK, P.W. Genetics of Populations. 3rd ed. Jones and Bartlett Publishers, Sudbury, MA, USA, 2004. 737p.
KEMPTHORNE, O. An Introduction to Genetic Statistics. The Iowa State University Press, Ames, IA, USA,1957.
LI, C.C. First course in population genetics. Boxwood Press, Pacific Grove, 1970. 631p.
LI, C.C. Population Genetics. University of Chicago Press, Chicago, IL, USA, 1955.
METTLER, L.E.; GREGG, T.G.; SCHAFFER, H.E. Genetics and Evolution. Prentice Hall, Eglewood Cliffs, NJ, USA, 1988.
NEI, M. Molecular Evolutionary Genetics. Columbia University Press, New York, NY, USA,1987. 512p.
RIDLEY, M. Evolução. 3ª ed. ArtMed Editora, Porto Alegre, RS, 2006. 752p.
TEMPLETON, A.R. Population Genetics and Microevolutionary Theory. John Wiley & Sons, Hoboken, NJ, USA, 2006. 705p.
WEIR, B.S. Genetics Data Analysis II: Methods for Discrete Population Genetic Data. Sinauer Associates, Sunderland, MA, USA, 1996. 376p.