LGN5830 - Biometria de Marcadores Genéticos

Carga Horária

Docentes responsáveis
Antonio Augusto Franco Garcia

Objetivo
Habilitar os alunos para que consigam analisar, interpretar e incorporar a informação fornecida pelos
marcadores genéticos em pesquisas de genética e melhoramento.

Conteúdo
Serão abordados tópicos que fazem parte da área conhecida como Genética Estatística, descritos a
seguir, para todos os tipos de populações de mapeamento (F2, RC, RILs, delineamento III e F1
segregante). Construção de mapas genéticos: teste da segregação mendeliana, análise de ligação
multiponto, ordenação dos locos, funções de mapeamento. Mapeamento de QTL's: análise de marcas
individuais, mapeamento por intervalo, mapeamento por intervalo composto, mapeamento de múltiplos
intervalos, mapeamento usando modelos mistos, mapeamento associativo. Seleção genômica:
fundamentação do GBLUP e demais métodos relevantes. Aplicação dos resultados para estudos de
heterose, QTL x E, correlação entre caracteres, etc. Os programas computacionais que serão usados
serão principalmente baseados no R, incluindo por exemplo OneMap, R/qtl, etc.

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